Most Affordable GLP-1 Weight Loss Programs Under $300/Month
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Ranked Providers
| Rank | Provider | Starting price language | Best for | CTA |
|---|---|---|---|---|
| 1 | Tmates | From $158/mo | Lowest advertised floor | /go/tmates |
| 2 | Henry Meds | From $179/mo | Budget cash-pay access | /go/henry-meds |
| 3 | ShedRx | From $199/mo (injections and lozenges) | Direct GLP-1 shoppers | /go/shedrx |
| 4 | Direct Meds | From $249/mo (sublingual) | Cash-pay medication access | /go/direct-meds |
| 5 | Mochi Health | From $79/mo membership; medication may be separate | Support plus membership model | /go/mochi-health |
| 6 | Sesame Care | Visit price varies; medication may be separate | Clinician visit first | /go/sesame-care |
ShedRx pricing verified 2026-09-03 from ShedRx’s live weight-loss category page (tryshed.com): compounded semaglutide injections from $199/mo, GLP-1 lozenges from $199/mo, liquid drops from $229/mo, compounded tirzepatide injections from $299/mo. Prices scale with dose, confirm current pricing at checkout.
Price Watchouts
“From $X/mo” is a floor price. It may reflect starter dose, membership only, limited plan terms, or a specific medication. Always confirm the actual month-two and month-three price before enrolling.
Top Pick
Tmates may have the lowest advertised floor, but ShedRx may be easier for many shoppers to compare directly. Henry Meds and Direct Meds are also worth reviewing if your target is under $300/month.
FAQ
Can GLP-1 programs cost under $300/month?
Some programs advertise starting prices under $300/month, but the total cost depends on medication, dose, visits, shipping, labs, and follow-up.
Are under-$300 GLP-1 programs compounded?
Many lower-cost cash-pay programs involve compounded medication pathways. Compounded medications are not FDA-approved finished products.
The FDA has proposed excluding semaglutide, tirzepatide, and liraglutide from the 503B bulk compounding list, citing no identified clinical need. The public comment period, extended to July 30, 2026, has now closed. If finalized, this could affect the availability, pricing, and continuity of some compounded GLP-1 programs. We will update this page as the regulatory situation develops.
What fees should I verify?
Verify medication, membership, clinician visits, labs, shipping, dose increases, refill support, and cancellation terms.
RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Content last updated July 16, 2026.
