Quick answer
Direct Meds and telos rx both offer GLP-1 telehealth, but they package medication, support, and pricing differently. The right choice depends on whether you weight cost, clinical touch, or formulation flexibility highest.
Side-by-side comparison
| Feature | Direct Meds | telos rx |
|---|---|---|
| Best for | Multiple compounded formats (injection and sublingual) | One integrated care team across GLP-1, hormones/longevity, sexual health, and recovery (peptide-led telehealth) rather than a single-indication weight-loss pure-play |
| Medication type | Compounded semaglutide and tirzepatide | Compounded semaglutide and tirzepatide (injectable, plus needle-free oral/sublingual and a microdosed tirzepatide) inside an integrated peptide-led telehealth menu; medical services by an independent US-licensed medical group (Arora Health Group) |
| Pricing model | All-inclusive monthly price by medication format | Cash-pay subscription with 'first month low as' intro pricing per medication; the ongoing recurring rate is NOT published on the public site (funnel-gated at start.telosrx.com) — no single defensible recurring price (Oak/LIV Body mechanism) |
| Semaglutide price | From $249/mo (sublingual) to $297/mo (injection), all-inclusive — verified 2026-07-16 on Direct Meds' own product pages ('$249.00 / month … Billed Every Month', '0% OFF') | Compounded — advertised 'first month low as $49'; ongoing recurring rate not published (funnel-gated), confirm at enrollment |
| Tirzepatide price | From $299/mo (sublingual) to $399/mo (injection), all-inclusive — verified 2026-07-16 | Compounded — injectable advertised 'first month low as $99'; oral 'first month low as $49'; microdosed 'first month low as $69'; ongoing recurring rate not published, confirm at enrollment |
| Key watchout | Pricing varies by format and page — product-page 'all-inclusive' rates differ from homepage promo cards; confirm your format's rate at checkout | telos publishes only 'first month low as' intro figures (semaglutide $49, tirzepatide $99, oral tirzepatide $49, microdosed tirzepatide $69); the ongoing monthly rate is not shown on the public site and is confirmed inside the intake flow — confirm the real recurring price at enrollment. State availability is not published, no dispensing pharmacy is named, and shipped compounded medication is non-refundable. |
When to choose Direct Meds
- You want a specific format — injection or sublingual — at a clear all-inclusive price
- You're already familiar with GLP-1 dosing and side-effect management
- You don't need a coach or a heavy-touch clinical team
- You want a no-frills, predictable monthly bill
Check current Direct Meds pricing →
When to choose telos rx
- You want one integrated care team across GLP-1 weight loss, longevity/energy (NAD+), recovery (sermorelin), and sexual health (PT-141) rather than a single-indication program
- You value an upfront 'compounded / not FDA-approved' disclosure and a LegitScript-certified telehealth platform
- You're comfortable confirming the real ongoing monthly price at enrollment (telos publishes only 'first month low as' intro figures)
- You want async care with a 5-minute online visit and a 100% refund if a clinician decides a GLP-1 isn't the right fit
Check current telos rx pricing →
Full reviews
Frequently asked questions
Is Direct Meds cheaper than telos rx?
telos rx starts lower on semaglutide (Compounded — advertised 'first month low as $49'; ongoing recurring rate not published (funnel-gated), confirm at enrollment). telos rx starts lower on tirzepatide (Compounded — injectable advertised 'first month low as $99'; oral 'first month low as $49'; microdosed 'first month low as $69'; ongoing recurring rate not published, confirm at enrollment). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide — Direct Meds or telos rx?
telos rx starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are Direct Meds and telos rx compounded or brand-name?
Direct Meds offers compounded semaglutide and tirzepatide. telos rx offers compounded semaglutide and tirzepatide (injectable, plus needle-free oral/sublingual and a microdosed tirzepatide) inside an integrated peptide-led telehealth menu; medical services by an independent us-licensed medical group (arora health group). If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Direct Meds to telos rx?
Yes — switching between Direct Meds and telos rx is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Direct Meds and telos rx to other programs
- Direct Meds vs ShedRx · telos rx vs ShedRx
- Direct Meds vs TMates · telos rx vs TMates
- Direct Meds vs Sprout Health · telos rx vs Sprout Health
- Direct Meds vs Mochi Health · telos rx vs Mochi Health
- Direct Meds vs Henry Meds · telos rx vs Henry Meds
- Direct Meds vs Calibrate · telos rx vs Calibrate
- Direct Meds vs Embody · telos rx vs Embody
- Direct Meds vs Found · telos rx vs Found
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RangeYourself is reader-supported. We may earn a commission when you click on certain links — at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like $249/mo (sublingual) to $297/mo (injection), all-inclusive — verified 2026-07-16 on Direct Meds' own product pages ('$249.00 / month … Billed Every Month', '0% OFF') and Compounded — advertised 'first month low as $49'; ongoing recurring rate not published (funnel-gated), confirm at enrollment are starting tiers, not your guaranteed long-term cost.