A multicultural group practicing yoga together in a bright studio

Enhance MD vs ShedRx: GLP-1 Comparison 2026

Enhance MD vs ShedRx: pricing, medication type, clinical support, and which mid-market GLP-1 patient each program fits. Both programs’ prices verified July 2026 or later; each price carries its own date in the table below.

By RangeYourselfUpdated September 3, 20264 min read

Quick answer

Enhance MD is a coaching-heavy, brand-name-leaning program; ShedRx is a more medication-first telehealth experience. Choose Enhance MD if you want behavior-change structure; choose ShedRx if you want straightforward GLP-1 access.

Side-by-side comparison

Feature	Enhance MD	ShedRx
Best for	Shoppers who want GLP-1 inside a fuller metabolic/NAD+ coaching program rather than medication-only	Broad GLP-1 menu and multiple formats
Medication type	Compounded GLP-1 (semaglutide, tirzepatide, combo, microdosing) offered inside a 'Metabolic Reset' program with NAD+ and coaching	Compounded and brand-name options
Pricing model	Premium metabolic-program subscription, the monthly price bundles medication, ongoing provider care, and lab testing (not GLP-1 alone)	Starting prices by product
Semaglutide price	Compounded, 'GLP-1 Core' $212/mo bundled program ($112 first month), verified 2026-07-14. Price reflects the metabolic program, not GLP-1 alone.	Compounded semaglutide injection $199/mo month-to-month, $179/mo on a 6-month plan, $159/mo on a 12-month plan (product page plan table, verified 2026-09-03 on tryshed.com/products/compounded-semaglutide-injections); the category page card simultaneously advertises 'Starting at $249/month' for the same product (verified same day) — Shed's own two surfaces disagree, both recorded. GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo, verified 2026-09-03 on tryshed.com/products/category/weight-loss
Tirzepatide price	Compounded, 'GLP-1 Advanced' $280/mo; combo 'GLP-1 Elite' $322/mo; microdosing tirzepatide $169/mo, all bundled-program prices, verified 2026-07-14.	From $349/mo (compounded injection), verified 2026-09-03 on tryshed.com/products/category/weight-loss (unchanged since 2026-07-21)
Key watchout	The $212–$322/mo figures are the BUNDLED program price, verified first-party to include '4 Weeks of Medication', 'Ongoing Provider Care & Support', and 'Metabolic Lab Testing Every 6 Months', NOT the cost of the GLP-1 medication alone. A first-month discount applies (e.g. $112 first month on GLP-1 Core).	Verify higher-dose pricing and exact formulation before checkout
Price checked	Checked by a person July 14, 2026 · an automated check re-read it September 3, 2026	Checked by a person September 3, 2026

When to choose Enhance MD

You want GLP-1 inside a structured metabolic program (provider care + periodic lab testing), not medication-only
You’re comparing NAD+/longevity-style programs, not just low-cost GLP-1
You value an upfront 'compounded / not FDA-approved' disclosure
You’re comfortable that the monthly price bundles services beyond the medication

Check current Enhance MD pricing →

When to choose ShedRx

You want both compounded and brand-name options on one menu
You prefer multiple formulation formats (injection, oral, sublingual where offered)
You're starting at a low dose and want a low entry price
You value being able to switch products without changing programs

Check current ShedRx pricing →

Full reviews

Frequently asked questions

Is Enhance MD cheaper than ShedRx?

ShedRx starts lower on semaglutide (Compounded semaglutide injection $199/mo month-to-month, $179/mo on a 6-month plan, $159/mo on a 12-month plan (product page plan table, verified 2026-09-03 on tryshed.com/products/compounded-semaglutide-injections); the category page card simultaneously advertises 'Starting at $249/month' for the same product (verified same day) — Shed's own two surfaces disagree, both recorded. GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo, verified 2026-09-03 on tryshed.com/products/category/weight-loss). Enhance MD starts lower on tirzepatide (Compounded, 'GLP-1 Advanced' $280/mo; combo 'GLP-1 Elite' $322/mo; microdosing tirzepatide $169/mo, all bundled-program prices, verified 2026-07-14.). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.

Which is better for semaglutide or tirzepatide, Enhance MD or ShedRx?

ShedRx tends to win on semaglutide entry pricing; Enhance MD tends to win on tirzepatide entry pricing. Pick by which medication you'll be on long-term, not by the cheapest entry tier.

Are Enhance MD and ShedRx compounded or brand-name?

Enhance MD offers compounded glp-1 (semaglutide, tirzepatide, combo, microdosing) offered inside a 'metabolic reset' program with nad+ and coaching. ShedRx offers compounded and brand-name options. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.

Can I switch from Enhance MD to ShedRx?

Yes, switching between Enhance MD and ShedRx is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.

Compare Enhance MD and ShedRx to other programs

Alert me when this gets cheaper

These prices move. Get one email when we publish a verified price drop, the programs on this list included. No spam. Unsubscribe any time.

Related guides

About compounded GLP-1 medicationsCompounded semaglutide and tirzepatide are not FDA-approved finished products. They are prepared by state-licensed 503A pharmacies or 503B outsourcing facilities and are not individually reviewed by the FDA for safety, effectiveness, or quality. Compounders describe these preparations as using the same active ingredient as the approved medicines; the FDA has warned that some compounded products use salt forms, semaglutide sodium or semaglutide acetate, that it considers different active ingredients from the approved drug, and has issued warning letters over marketing that presents a compounded preparation as interchangeable with an approved one. The FDA declared the semaglutide shortage resolved on February 21, 2025 and the tirzepatide shortage resolved in December 2024, so the shortage-era pathway for broad compounding of these drugs has ended. Compounding now proceeds under the ordinary rules: a 503A pharmacy compounding for an individual patient on a prescription, or a 503B outsourcing facility, which compounds in bulk under CGMP and FDA registration rather than per patient. Those rules generally do not cover a product that is “essentially a copy” of an approved drug unless a prescriber documents a change that makes a significant difference for an individual patient. Talk to a clinician about contraindications including personal or family history of medullary thyroid carcinoma or MEN 2. RangeYourself does not provide medical advice, does not guarantee a prescription, and does not guarantee weight-loss results.

RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers, verified on the dates shown in the table above, and may change. Numbers like Compounded, 'GLP-1 Core' $212/mo bundled program ($112 first month), verified 2026-07-14. Price reflects the metabolic program, not GLP-1 alone. and Compounded semaglutide injection $199/mo month-to-month, $179/mo on a 6-month plan, $159/mo on a 12-month plan (product page plan table, verified 2026-09-03 on tryshed.com/products/compounded-semaglutide-injections); the category page card simultaneously advertises 'Starting at $249/month' for the same product (verified same day) — Shed's own two surfaces disagree, both recorded. GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo, verified 2026-09-03 on tryshed.com/products/category/weight-loss are starting tiers, not your guaranteed long-term cost.