Quick answer
Yucca Health typically wins on sticker price for compounded GLP-1, while Enhance MD bundles more clinical support and often a wider menu of options. Choose Yucca Health if you're price-first; choose Enhance MD if you want hands-on prescribing or brand-name access.
Side-by-side comparison
| Feature | Enhance MD | Yucca Health |
|---|---|---|
| Best for | Shoppers who want GLP-1 inside a fuller metabolic/NAD+ coaching program rather than medication-only | Low advertised entry price on compounded GLP-1 with plain FDA disclosures and all-50-state provider coverage |
| Medication type | Compounded GLP-1 (semaglutide, tirzepatide, combo, microdosing) offered inside a 'Metabolic Reset' program with NAD+ and coaching | Compounded semaglutide and tirzepatide, once-weekly injection ('Semaglutide+' / 'Tirzepatide+'); also sells NAD+ and Sermorelin (out of registry scope) |
| Pricing model | Premium metabolic-program subscription, the monthly price bundles medication, ongoing provider care, and lab testing (not GLP-1 alone) | 6-month prescription plans billed monthly/quarterly/6-month; advertised new-patient entry pricing; full pricing shared after intake |
| Semaglutide price | Compounded, 'GLP-1 Core' $212/mo bundled program ($112 first month), verified 2026-07-14. Price reflects the metabolic program, not GLP-1 alone. | Compounded, '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated) |
| Tirzepatide price | Compounded, 'GLP-1 Advanced' $280/mo; combo 'GLP-1 Elite' $322/mo; microdosing tirzepatide $169/mo, all bundled-program prices, verified 2026-07-14. | Compounded, '$258 /mo 6 month supply' (new-patient 6-month plan entry rate; full pricing intake-gated) |
| Key watchout | The $212–$322/mo figures are the BUNDLED program price, verified first-party to include '4 Weeks of Medication', 'Ongoing Provider Care & Support', and 'Metabolic Lab Testing Every 6 Months', NOT the cost of the GLP-1 medication alone. A first-month discount applies (e.g. $112 first month on GLP-1 Core). | The $146/mo figure is a NEW-PATIENT 'as low as' rate on a 6-month semaglutide plan, shown site-wide with an 'Exclusive Lifetime Offer' promo code (YUCCA4LIFE), Yucca's own FAQ says full pricing 'is shared after intake once eligibility is confirmed.' Confirm your dose's ongoing rate at intake. Pharmacies are not named. |
When to choose Enhance MD
- You want GLP-1 inside a structured metabolic program (provider care + periodic lab testing), not medication-only
- You’re comparing NAD+/longevity-style programs, not just low-cost GLP-1
- You value an upfront 'compounded / not FDA-approved' disclosure
- You’re comfortable that the monthly price bundles services beyond the medication
Check current Enhance MD pricing →
When to choose Yucca Health
- You want a low advertised entry price on compounded semaglutide or tirzepatide
- You value an upfront 'not FDA-approved' compounding disclosure in the FAQ
- You want provider coverage in all 50 states with free 2-day shipping
- You're comfortable confirming your exact ongoing rate at intake (pricing beyond the entry offer is shared after eligibility)
Check current Yucca Health pricing →
Full reviews
Frequently asked questions
Is Enhance MD cheaper than Yucca Health?
Yucca Health starts lower on semaglutide (Compounded, '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated)). Yucca Health starts lower on tirzepatide (Compounded, '$258 /mo 6 month supply' (new-patient 6-month plan entry rate; full pricing intake-gated)). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide, Enhance MD or Yucca Health?
Yucca Health starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are Enhance MD and Yucca Health compounded or brand-name?
Enhance MD offers compounded glp-1 (semaglutide, tirzepatide, combo, microdosing) offered inside a 'metabolic reset' program with nad+ and coaching. Yucca Health offers compounded semaglutide and tirzepatide, once-weekly injection ('semaglutide+' / 'tirzepatide+'); also sells nad+ and sermorelin (out of registry scope). If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Enhance MD to Yucca Health?
Yes, switching between Enhance MD and Yucca Health is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Enhance MD and Yucca Health to other programs
- Enhance MD vs ShedRx · Yucca Health vs ShedRx
- Enhance MD vs TMates · Yucca Health vs TMates
- Enhance MD vs Direct Meds · Yucca Health vs Direct Meds
- Enhance MD vs Sprout Health · Yucca Health vs Sprout Health
- Enhance MD vs Mochi Health · Yucca Health vs Mochi Health
- Enhance MD vs Henry Meds · Yucca Health vs Henry Meds
- Enhance MD vs Calibrate · Yucca Health vs Calibrate
- Enhance MD vs Embody · Yucca Health vs Embody
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RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like Compounded, 'GLP-1 Core' $212/mo bundled program ($112 first month), verified 2026-07-14. Price reflects the metabolic program, not GLP-1 alone. and Compounded, '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated) are starting tiers, not your guaranteed long-term cost.
