Quick answer
Yucca Health typically wins on sticker price for compounded GLP-1, while ShedRx bundles more clinical support and often a wider menu of options. Choose Yucca Health if you're price-first; choose ShedRx if you want hands-on prescribing or brand-name access.
Side-by-side comparison
| Feature | ShedRx | Yucca Health |
|---|---|---|
| Best for | Broad GLP-1 menu and multiple formats | Low advertised entry price on compounded GLP-1 with plain FDA disclosures and all-50-state provider coverage |
| Medication type | Compounded and brand-name options | Compounded semaglutide and tirzepatide — once-weekly injection ('Semaglutide+' / 'Tirzepatide+'); also sells NAD+ and Sermorelin (out of registry scope) |
| Pricing model | Starting prices by product | 6-month prescription plans billed monthly/quarterly/6-month; advertised new-patient entry pricing; full pricing shared after intake |
| Semaglutide price | From $249/mo (compounded injection); GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo — verified 2026-07-21 on tryshed.com/products/category/weight-loss | Compounded — '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated) |
| Tirzepatide price | From $349/mo (compounded injection) — verified 2026-07-21 on tryshed.com/products/category/weight-loss | Compounded — '$258 /mo 6 month supply' (new-patient 6-month plan entry rate; full pricing intake-gated) |
| Key watchout | Verify higher-dose pricing and exact formulation before checkout | The $146/mo figure is a NEW-PATIENT 'as low as' rate on a 6-month semaglutide plan, shown site-wide with an 'Exclusive Lifetime Offer' promo code (YUCCA4LIFE) — Yucca's own FAQ says full pricing 'is shared after intake once eligibility is confirmed.' Confirm your dose's ongoing rate at intake. Pharmacies are not named. |
When to choose ShedRx
- You want both compounded and brand-name options on one menu
- You prefer multiple formulation formats (injection, oral, sublingual where offered)
- You're starting at a low dose and want a low entry price
- You value being able to switch products without changing programs
Check current ShedRx pricing →
When to choose Yucca Health
- You want a low advertised entry price on compounded semaglutide or tirzepatide
- You value an upfront 'not FDA-approved' compounding disclosure in the FAQ
- You want provider coverage in all 50 states with free 2-day shipping
- You're comfortable confirming your exact ongoing rate at intake (pricing beyond the entry offer is shared after eligibility)
Check current Yucca Health pricing →
Full reviews
Frequently asked questions
Is ShedRx cheaper than Yucca Health?
Yucca Health starts lower on semaglutide (Compounded — '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated)). Yucca Health starts lower on tirzepatide (Compounded — '$258 /mo 6 month supply' (new-patient 6-month plan entry rate; full pricing intake-gated)). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide — ShedRx or Yucca Health?
Yucca Health starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are ShedRx and Yucca Health compounded or brand-name?
ShedRx offers compounded and brand-name options. Yucca Health offers compounded semaglutide and tirzepatide — once-weekly injection ('semaglutide+' / 'tirzepatide+'); also sells nad+ and sermorelin (out of registry scope). If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from ShedRx to Yucca Health?
Yes — switching between ShedRx and Yucca Health is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare ShedRx and Yucca Health to other programs
- ShedRx vs TMates · Yucca Health vs TMates
- ShedRx vs Direct Meds · Yucca Health vs Direct Meds
- ShedRx vs Sprout Health · Yucca Health vs Sprout Health
- ShedRx vs Mochi Health · Yucca Health vs Mochi Health
- ShedRx vs Henry Meds · Yucca Health vs Henry Meds
- ShedRx vs Calibrate · Yucca Health vs Calibrate
- ShedRx vs Embody · Yucca Health vs Embody
- ShedRx vs Found · Yucca Health vs Found
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RangeYourself is reader-supported. We may earn a commission when you click on certain links — at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like $249/mo (compounded injection); GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo — verified 2026-07-21 on tryshed.com/products/category/weight-loss and Compounded — '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated) are starting tiers, not your guaranteed long-term cost.