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HealthRX vs TMates: GLP-1 Comparison 2026

HealthRX vs TMates: pricing, medication type, clinical support, and which budget-conscious GLP-1 patient each program fits. Both programs’ prices verified July 2026 or later; each price carries its own date in the table below.

By RangeYourselfUpdated August 21, 20264 min read

Quick answer

HealthRX typically wins on sticker price for compounded GLP-1. Both prescribe compounded medication, so compare them on the specific product, plan term, and terms you'd actually be buying rather than on program positioning.

Side-by-side comparison

Feature	HealthRX	TMates
Best for	A low, transparent flat price on compounded GLP-1 with no insurance and fast shipping	Compounded GLP-1 with hands-on clinical touch
Medication type	Compounded semaglutide and tirzepatide (503A)	Compounded GLP-1 with bundled clinical support
Pricing model	Commitment-tier plans (3/6/12-month), one flat price at every dose	Monthly subscription, dose-tier pricing
Semaglutide price	Compounded, $99/mo on the 12-month plan; from $133/mo on the 3-month plan, verified 2026-08-21 on healthrx.com (unchanged since 2026-07-18). Same price at every dose.	From $158/mo (compounded semaglutide, 12-month plan; $249/mo month-to-month); medication and visits included
Tirzepatide price	Compounded, $179/mo on the 12-month plan; from $209/mo on the 3-month plan, verified 2026-08-21 on healthrx.com (unchanged since 2026-07-18). Same price at every dose.	From $167/mo (compounded tirzepatide, 12-month plan; $297/mo month-to-month)
Key watchout	The lowest advertised rate requires the 12-month commitment plan; the 3-month plan is the higher entry tier, and any 1-month option is not publicly priced. Confirm your plan term and dose price at checkout.	The $158 headline is the compounded SEMAGLUTIDE plan (12-month term; $249/mo month-to-month). Tirzepatide costs more ($167/mo on a 12-month plan, $297 month-to-month), confirm your product and term at checkout
Price checked	Checked by a person August 21, 2026 · an automated check re-read it September 3, 2026	Checked by a person July 14, 2026 · an automated check re-read it September 3, 2026

When to choose HealthRX

You want a low, transparent flat price on compounded semaglutide or tirzepatide with no insurance required
You're comfortable committing to a 3- or 12-month plan to lock the lowest per-month rate
You want the same price at every dose as you escalate
You value fast cold-chain shipping to all 50 states

Check current HealthRX pricing →

When to choose TMates

You want a compounded program with clinical check-ins built in
You'd rather pay one bundled monthly fee than line items
You want responsive messaging with prescribers
You're comfortable with a longer onboarding intake in exchange for support

Check current TMates pricing →

Full reviews

Frequently asked questions

Is HealthRX cheaper than TMates?

HealthRX starts lower on semaglutide (Compounded, $99/mo on the 12-month plan; from $133/mo on the 3-month plan, verified 2026-08-21 on healthrx.com (unchanged since 2026-07-18). Same price at every dose.). TMates starts lower on tirzepatide (From $167/mo (compounded tirzepatide, 12-month plan; $297/mo month-to-month)). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.

Which is better for semaglutide or tirzepatide, HealthRX or TMates?

HealthRX tends to win on semaglutide entry pricing; TMates tends to win on tirzepatide entry pricing. Pick by which medication you'll be on long-term, not by the cheapest entry tier.

Are HealthRX and TMates compounded or brand-name?

HealthRX offers compounded semaglutide and tirzepatide (503a). TMates offers compounded glp-1 with bundled clinical support. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.

Can I switch from HealthRX to TMates?

Yes, switching between HealthRX and TMates is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.

Compare HealthRX and TMates to other programs

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Related guides

About compounded GLP-1 medicationsCompounded semaglutide and tirzepatide are not FDA-approved finished products. They are prepared by state-licensed 503A pharmacies or 503B outsourcing facilities and are not individually reviewed by the FDA for safety, effectiveness, or quality. Compounders describe these preparations as using the same active ingredient as the approved medicines; the FDA has warned that some compounded products use salt forms, semaglutide sodium or semaglutide acetate, that it considers different active ingredients from the approved drug, and has issued warning letters over marketing that presents a compounded preparation as interchangeable with an approved one. The FDA declared the semaglutide shortage resolved on February 21, 2025 and the tirzepatide shortage resolved in December 2024, so the shortage-era pathway for broad compounding of these drugs has ended. Compounding now proceeds under the ordinary rules: a 503A pharmacy compounding for an individual patient on a prescription, or a 503B outsourcing facility, which compounds in bulk under CGMP and FDA registration rather than per patient. Those rules generally do not cover a product that is “essentially a copy” of an approved drug unless a prescriber documents a change that makes a significant difference for an individual patient. Talk to a clinician about contraindications including personal or family history of medullary thyroid carcinoma or MEN 2. RangeYourself does not provide medical advice, does not guarantee a prescription, and does not guarantee weight-loss results.

RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers, verified on the dates shown in the table above, and may change. Numbers like Compounded, $99/mo on the 12-month plan; from $133/mo on the 3-month plan, verified 2026-08-21 on healthrx.com (unchanged since 2026-07-18). Same price at every dose. and $158/mo (compounded semaglutide, 12-month plan; $249/mo month-to-month); medication and visits included are starting tiers, not your guaranteed long-term cost.