Quick answer
Oak and Synergy Rx both offer GLP-1 telehealth, but they package medication, support, and pricing differently. The right choice depends on whether you weight cost, clinical touch, or formulation flexibility highest.
Side-by-side comparison
| Feature | Oak | Synergy Rx |
|---|---|---|
| Best for | Compounded GLP-1 shoppers comparing cash-pay options | All-50-state compounded GLP-1 shoppers comparing broad menus with named pharmacies |
| Medication type | Compounded semaglutide and tirzepatide, injectable and sublingual (Oak Longevity) | Compounded semaglutide and tirzepatide, injectable and oral; once-weekly at-home injection |
| Pricing model | Cash-pay subscription; recurring price not consistently listed publicly (advertised $119–$190/mo under promos) | Cash-pay subscription; advertised 'starting at' entry pricing with a live '2026 Promo Applied' banner and a $100 welcome credit |
| Semaglutide price | Compounded, advertised from $119/mo (promo); recurring rate not consistently listed, confirm in enrollment | Compounded, injectable 'starting at $199/mo', oral 'starting at $299/mo' (advertised starting price, verified 2026-07-14; '2026 Promo Applied' banner active). |
| Tirzepatide price | Compounded, advertised from $185/mo (promo); recurring rate not consistently listed, confirm in enrollment | Compounded, injectable 'starting at $349/mo', oral 'starting at $399/mo' (advertised starting price, verified 2026-07-14). |
| Key watchout | Oak advertises figures from $119 to $190/mo across its own pages under promotions and does not list one consistent recurring price, confirm the exact ongoing rate in the enrollment flow before subscribing. Fees are non-refundable once charged. | The $199 semaglutide figure is an advertised 'starting at' entry price shown with a live '2026 Promo Applied' banner and a $100 welcome credit, confirm the exact ongoing rate and whether the promo is active at enrollment. Injectable tirzepatide starts at $349; oral formats cost more. |
When to choose Oak
- You want compounded semaglutide or tirzepatide (injectable or sublingual) on a cash-pay plan
- You're comfortable confirming the exact recurring price in Oak's enrollment flow rather than on the public site
- You prefer async care with no video visit required
- You want same-day provider review and free shipping
When to choose Synergy Rx
- You want compounded semaglutide or tirzepatide (injectable or oral) on a cash-pay plan in all 50 states
- You value named dispensing pharmacies (Belmar, Strive, Epiq Scripts, Casa Pharma Rx)
- You value an upfront compounding disclosure in the FAQ
- You’re comfortable confirming the exact ongoing rate (the $199 is an advertised 'starting at' with a promo banner)
Check current Synergy Rx pricing →
Full reviews
Frequently asked questions
Is Oak cheaper than Synergy Rx?
Oak starts lower on semaglutide (Compounded, advertised from $119/mo (promo); recurring rate not consistently listed, confirm in enrollment). Oak starts lower on tirzepatide (Compounded, advertised from $185/mo (promo); recurring rate not consistently listed, confirm in enrollment). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide, Oak or Synergy Rx?
Oak starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are Oak and Synergy Rx compounded or brand-name?
Oak offers compounded semaglutide and tirzepatide, injectable and sublingual (oak longevity). Synergy Rx offers compounded semaglutide and tirzepatide, injectable and oral; once-weekly at-home injection. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Oak to Synergy Rx?
Yes, switching between Oak and Synergy Rx is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Oak and Synergy Rx to other programs
- Oak vs ShedRx · Synergy Rx vs ShedRx
- Oak vs TMates · Synergy Rx vs TMates
- Oak vs Direct Meds · Synergy Rx vs Direct Meds
- Oak vs Sprout Health · Synergy Rx vs Sprout Health
- Oak vs Mochi Health · Synergy Rx vs Mochi Health
- Oak vs Henry Meds · Synergy Rx vs Henry Meds
- Oak vs Calibrate · Synergy Rx vs Calibrate
- Oak vs Embody · Synergy Rx vs Embody
Related guides
RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like Compounded, advertised from $119/mo (promo); recurring rate not consistently listed, confirm in enrollment and Compounded, injectable 'starting at $199/mo', oral 'starting at $299/mo' (advertised starting price, verified 2026-07-14; '2026 Promo Applied' banner active). are starting tiers, not your guaranteed long-term cost.