Quick answer
ShedRx and Synergy Rx both offer GLP-1 telehealth, but they package medication, support, and pricing differently. The right choice depends on whether you weight cost, clinical touch, or formulation flexibility highest.
Side-by-side comparison
| Feature | ShedRx | Synergy Rx |
|---|---|---|
| Best for | Broad GLP-1 menu and multiple formats | All-50-state compounded GLP-1 shoppers comparing broad menus with named pharmacies |
| Medication type | Compounded and brand-name options | Compounded semaglutide and tirzepatide — injectable and oral; once-weekly at-home injection |
| Pricing model | Starting prices by product | Cash-pay subscription; advertised 'starting at' entry pricing with a live '2026 Promo Applied' banner and a $100 welcome credit |
| Semaglutide price | From $249/mo (compounded injection); GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo — verified 2026-07-21 on tryshed.com/products/category/weight-loss | Compounded — injectable 'starting at $199/mo', oral 'starting at $299/mo' (advertised starting price, verified 2026-07-14; '2026 Promo Applied' banner active). |
| Tirzepatide price | From $349/mo (compounded injection) — verified 2026-07-21 on tryshed.com/products/category/weight-loss | Compounded — injectable 'starting at $349/mo', oral 'starting at $399/mo' (advertised starting price, verified 2026-07-14). |
| Key watchout | Verify higher-dose pricing and exact formulation before checkout | The $199 semaglutide figure is an advertised 'starting at' entry price shown with a live '2026 Promo Applied' banner and a $100 welcome credit — confirm the exact ongoing rate and whether the promo is active at enrollment. Injectable tirzepatide starts at $349; oral formats cost more. |
When to choose ShedRx
- You want both compounded and brand-name options on one menu
- You prefer multiple formulation formats (injection, oral, sublingual where offered)
- You're starting at a low dose and want a low entry price
- You value being able to switch products without changing programs
Check current ShedRx pricing →
When to choose Synergy Rx
- You want compounded semaglutide or tirzepatide (injectable or oral) on a cash-pay plan in all 50 states
- You value named dispensing pharmacies (Belmar, Strive, Epiq Scripts, Casa Pharma Rx)
- You value an upfront compounding disclosure in the FAQ
- You’re comfortable confirming the exact ongoing rate (the $199 is an advertised 'starting at' with a promo banner)
Check current Synergy Rx pricing →
Full reviews
Frequently asked questions
Is ShedRx cheaper than Synergy Rx?
Synergy Rx starts lower on semaglutide (Compounded — injectable 'starting at $199/mo', oral 'starting at $299/mo' (advertised starting price, verified 2026-07-14; '2026 Promo Applied' banner active).). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide — ShedRx or Synergy Rx?
Both ShedRx and Synergy Rx prescribe semaglutide and tirzepatide where appropriate. Choose based on how each program handles your target medication, not just the entry price.
Are ShedRx and Synergy Rx compounded or brand-name?
ShedRx offers compounded and brand-name options. Synergy Rx offers compounded semaglutide and tirzepatide — injectable and oral; once-weekly at-home injection. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from ShedRx to Synergy Rx?
Yes — switching between ShedRx and Synergy Rx is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare ShedRx and Synergy Rx to other programs
- ShedRx vs TMates · Synergy Rx vs TMates
- ShedRx vs Direct Meds · Synergy Rx vs Direct Meds
- ShedRx vs Sprout Health · Synergy Rx vs Sprout Health
- ShedRx vs Mochi Health · Synergy Rx vs Mochi Health
- ShedRx vs Henry Meds · Synergy Rx vs Henry Meds
- ShedRx vs Calibrate · Synergy Rx vs Calibrate
- ShedRx vs Embody · Synergy Rx vs Embody
- ShedRx vs Found · Synergy Rx vs Found
Related guides
RangeYourself is reader-supported. We may earn a commission when you click on certain links — at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like $249/mo (compounded injection); GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo — verified 2026-07-21 on tryshed.com/products/category/weight-loss and Compounded — injectable 'starting at $199/mo', oral 'starting at $299/mo' (advertised starting price, verified 2026-07-14; '2026 Promo Applied' banner active). are starting tiers, not your guaranteed long-term cost.