Quick answer
Trimi typically wins on sticker price for compounded GLP-1, while Oak bundles more clinical support and often a wider menu of options. Choose Trimi if you're price-first; choose Oak if you want hands-on prescribing or brand-name access.
Side-by-side comparison
| Feature | Oak | Trimi |
|---|---|---|
| Best for | Compounded GLP-1 shoppers comparing cash-pay options | Lowest-cost compounded GLP-1 on an annual plan with a plain 503A disclosure |
| Medication type | Compounded semaglutide and tirzepatide, injectable and sublingual (Oak Longevity) | Compounded semaglutide and compounded tirzepatide, once-weekly at-home injection |
| Pricing model | Cash-pay subscription; recurring price not consistently listed publicly (advertised $119–$190/mo under promos) | Flat-membership subscription billed yearly (annual commitment tier); one price covers medication, clinician visits, check-ins, shipping; no separate membership fee; no insurance |
| Semaglutide price | Compounded, advertised from $119/mo (promo); recurring rate not consistently listed, confirm in enrollment | Compounded, $99/mo on the annual plan, BILLED YEARLY ($1,188/yr up front). Verified 2026-07-14. |
| Tirzepatide price | Compounded, advertised from $185/mo (promo); recurring rate not consistently listed, confirm in enrollment | Compounded, $125/mo on the annual plan (billed yearly). Verified 2026-07-14. |
| Key watchout | Oak advertises figures from $119 to $190/mo across its own pages under promotions and does not list one consistent recurring price, confirm the exact ongoing rate in the enrollment flow before subscribing. Fees are non-refundable once charged. | The $99/mo semaglutide and $125/mo tirzepatide rates are the ANNUAL plan, BILLED YEARLY (semaglutide = $1,188 charged up front). A month-to-month rate is not published, confirm billing terms before enrolling. |
When to choose Oak
- You want compounded semaglutide or tirzepatide (injectable or sublingual) on a cash-pay plan
- You're comfortable confirming the exact recurring price in Oak's enrollment flow rather than on the public site
- You prefer async care with no video visit required
- You want same-day provider review and free shipping
When to choose Trimi
- You want the lowest-cost compounded semaglutide ($99/mo) or tirzepatide ($125/mo) with everything bundled
- You’re comfortable with an annual plan billed yearly ($1,188 up front for semaglutide)
- You value an upfront '503A compounding pharmacy' and 'not FDA-approved' disclosure
- You want care via a 50-state clinical network (Arora Health) with free shipping
Full reviews
Frequently asked questions
Is Oak cheaper than Trimi?
Trimi starts lower on semaglutide (Compounded, $99/mo on the annual plan, BILLED YEARLY ($1,188/yr up front). Verified 2026-07-14.). Trimi starts lower on tirzepatide (Compounded, $125/mo on the annual plan (billed yearly). Verified 2026-07-14.). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide, Oak or Trimi?
Trimi starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are Oak and Trimi compounded or brand-name?
Oak offers compounded semaglutide and tirzepatide, injectable and sublingual (oak longevity). Trimi offers compounded semaglutide and compounded tirzepatide, once-weekly at-home injection. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Oak to Trimi?
Yes, switching between Oak and Trimi is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Oak and Trimi to other programs
- Oak vs ShedRx · Trimi vs ShedRx
- Oak vs TMates · Trimi vs TMates
- Oak vs Direct Meds · Trimi vs Direct Meds
- Oak vs Sprout Health · Trimi vs Sprout Health
- Oak vs Mochi Health · Trimi vs Mochi Health
- Oak vs Henry Meds · Trimi vs Henry Meds
- Oak vs Calibrate · Trimi vs Calibrate
- Oak vs Embody · Trimi vs Embody
Related guides
RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like Compounded, advertised from $119/mo (promo); recurring rate not consistently listed, confirm in enrollment and Compounded, $99/mo on the annual plan, BILLED YEARLY ($1,188/yr up front). Verified 2026-07-14. are starting tiers, not your guaranteed long-term cost.