Quick answer
Strut Health typically wins on sticker price for compounded GLP-1, while TMates bundles more clinical support and often a wider menu of options. Choose Strut Health if you're price-first; choose TMates if you want hands-on prescribing or brand-name access.
Side-by-side comparison
| Feature | Strut Health | TMates |
|---|---|---|
| Best for | Low-cost compounded GLP-1 with plain compounding disclosures | Compounded GLP-1 with hands-on clinical touch |
| Medication type | Compounded semaglutide and tirzepatide — sublingual/oral and once-weekly injection | Compounded GLP-1 with bundled clinical support |
| Pricing model | Monthly auto-refill subscription; dose-tier 'starting at' entry pricing; medical-necessity gated | Monthly subscription, dose-tier pricing |
| Semaglutide price | Compounded — sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing) | From $158/mo (compounded semaglutide, 12-month plan; $249/mo month-to-month); medication and visits included |
| Tirzepatide price | Compounded — injectable from $199/mo; oral lozenge from $199/mo (lozenge only if a GLP-1 injection fails or can't be used) | From $167/mo (compounded tirzepatide, 12-month plan; $297/mo month-to-month) |
| Key watchout | Entry prices are the lowest-dose auto-refill rate — higher doses cost more, so confirm your dose at intake. Oral/sublingual and lozenge options require you to have failed or be unable to use an injectable GLP-1. | The $158 headline is the compounded SEMAGLUTIDE plan (12-month term; $249/mo month-to-month). Tirzepatide costs more ($167/mo on a 12-month plan, $297 month-to-month) — confirm your product and term at checkout |
When to choose Strut Health
- You want low-cost compounded semaglutide or tirzepatide with medication included
- You value upfront 'compounded / not FDA-approved' disclosures and a PCAB-accredited pharmacy
- You're comfortable with async-only care (no video visit) and a medical-necessity screen
- You want to cancel, pause, or delay your subscription anytime
Check current Strut Health pricing →
When to choose TMates
- You want a compounded program with clinical check-ins built in
- You'd rather pay one bundled monthly fee than line items
- You want responsive messaging with prescribers
- You're comfortable with a longer onboarding intake in exchange for support
Check current TMates pricing →
Full reviews
Frequently asked questions
Is Strut Health cheaper than TMates?
Strut Health starts lower on semaglutide (Compounded — sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing)). TMates starts lower on tirzepatide (From $167/mo (compounded tirzepatide, 12-month plan; $297/mo month-to-month)). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide — Strut Health or TMates?
Strut Health tends to win on semaglutide entry pricing; TMates tends to win on tirzepatide entry pricing. Pick by which medication you'll be on long-term, not by the cheapest entry tier.
Are Strut Health and TMates compounded or brand-name?
Strut Health offers compounded semaglutide and tirzepatide — sublingual/oral and once-weekly injection. TMates offers compounded glp-1 with bundled clinical support. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Strut Health to TMates?
Yes — switching between Strut Health and TMates is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Strut Health and TMates to other programs
- Strut Health vs ShedRx · TMates vs ShedRx
- Strut Health vs Direct Meds · TMates vs Direct Meds
- Strut Health vs Sprout Health · TMates vs Sprout Health
- Strut Health vs Mochi Health · TMates vs Mochi Health
- Strut Health vs Henry Meds · TMates vs Henry Meds
- Strut Health vs Calibrate · TMates vs Calibrate
- Strut Health vs Embody · TMates vs Embody
- Strut Health vs Found · TMates vs Found
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RangeYourself is reader-supported. We may earn a commission when you click on certain links — at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like Compounded — sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing) and $158/mo (compounded semaglutide, 12-month plan; $249/mo month-to-month); medication and visits included are starting tiers, not your guaranteed long-term cost.