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Strut Health vs TMates: GLP-1 Comparison 2026

Strut Health vs TMates: pricing, medication type, clinical support, and which budget-conscious GLP-1 patient each program fits. Both programs’ prices verified July 2026 or later; each price carries its own date in the table below.

By RangeYourselfUpdated August 21, 20264 min read

Quick answer

Strut Health typically wins on sticker price for compounded GLP-1. Both prescribe compounded medication, so compare them on the specific product, plan term, and terms you'd actually be buying rather than on program positioning.

Side-by-side comparison

Feature	Strut Health	TMates
Best for	Low-cost compounded GLP-1 with plain compounding disclosures	Compounded GLP-1 with hands-on clinical touch
Medication type	Compounded semaglutide and tirzepatide, sublingual/oral and once-weekly injection	Compounded GLP-1 with bundled clinical support
Pricing model	Monthly auto-refill subscription; dose-tier 'starting at' entry pricing; medical-necessity gated	Monthly subscription, dose-tier pricing
Semaglutide price	Compounded, sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing)	From $158/mo (compounded semaglutide, 12-month plan; $249/mo month-to-month); medication and visits included
Tirzepatide price	Compounded, injectable from $149/mo (price cut from $199, re-verified 2026-08-21); oral lozenge from $199/mo (lozenge only if a GLP-1 injection fails or can't be used)	From $167/mo (compounded tirzepatide, 12-month plan; $297/mo month-to-month)
Key watchout	Entry prices are the lowest-dose auto-refill rate, higher doses cost more, so confirm your dose at intake. Oral/sublingual and lozenge options require you to have failed or be unable to use an injectable GLP-1.	The $158 headline is the compounded SEMAGLUTIDE plan (12-month term; $249/mo month-to-month). Tirzepatide costs more ($167/mo on a 12-month plan, $297 month-to-month), confirm your product and term at checkout
Price checked	Checked by a person August 21, 2026 · an automated check re-read it September 3, 2026	Checked by a person July 14, 2026 · an automated check re-read it September 3, 2026

When to choose Strut Health

You want low-cost compounded semaglutide or tirzepatide with medication included
You value upfront 'compounded / not FDA-approved' disclosures and a PCAB-accredited pharmacy
You're comfortable with async-only care (no video visit) and a medical-necessity screen
You want to cancel, pause, or delay your subscription anytime

Check current Strut Health pricing →

When to choose TMates

You want a compounded program with clinical check-ins built in
You'd rather pay one bundled monthly fee than line items
You want responsive messaging with prescribers
You're comfortable with a longer onboarding intake in exchange for support

Check current TMates pricing →

Full reviews

Frequently asked questions

Is Strut Health cheaper than TMates?

Strut Health starts lower on semaglutide (Compounded, sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing)). Strut Health starts lower on tirzepatide (Compounded, injectable from $149/mo (price cut from $199, re-verified 2026-08-21); oral lozenge from $199/mo (lozenge only if a GLP-1 injection fails or can't be used)). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.

Which is better for semaglutide or tirzepatide, Strut Health or TMates?

Strut Health starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.

Are Strut Health and TMates compounded or brand-name?

Strut Health offers compounded semaglutide and tirzepatide, sublingual/oral and once-weekly injection. TMates offers compounded glp-1 with bundled clinical support. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.

Can I switch from Strut Health to TMates?

Yes, switching between Strut Health and TMates is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.

Compare Strut Health and TMates to other programs

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Related guides

About compounded GLP-1 medicationsCompounded semaglutide and tirzepatide are not FDA-approved finished products. They are prepared by state-licensed 503A pharmacies or 503B outsourcing facilities and are not individually reviewed by the FDA for safety, effectiveness, or quality. Compounders describe these preparations as using the same active ingredient as the approved medicines; the FDA has warned that some compounded products use salt forms, semaglutide sodium or semaglutide acetate, that it considers different active ingredients from the approved drug, and has issued warning letters over marketing that presents a compounded preparation as interchangeable with an approved one. The FDA declared the semaglutide shortage resolved on February 21, 2025 and the tirzepatide shortage resolved in December 2024, so the shortage-era pathway for broad compounding of these drugs has ended. Compounding now proceeds under the ordinary rules: a 503A pharmacy compounding for an individual patient on a prescription, or a 503B outsourcing facility, which compounds in bulk under CGMP and FDA registration rather than per patient. Those rules generally do not cover a product that is “essentially a copy” of an approved drug unless a prescriber documents a change that makes a significant difference for an individual patient. Talk to a clinician about contraindications including personal or family history of medullary thyroid carcinoma or MEN 2. RangeYourself does not provide medical advice, does not guarantee a prescription, and does not guarantee weight-loss results.

RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers, verified on the dates shown in the table above, and may change. Numbers like Compounded, sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing) and $158/mo (compounded semaglutide, 12-month plan; $249/mo month-to-month); medication and visits included are starting tiers, not your guaranteed long-term cost.