Quick answer
Strut Health typically wins on sticker price for compounded GLP-1, while Direct Meds bundles more clinical support and often a wider menu of options. Choose Strut Health if you're price-first; choose Direct Meds if you want hands-on prescribing or brand-name access.
Side-by-side comparison
| Feature | Direct Meds | Strut Health |
|---|---|---|
| Best for | Multiple compounded formats (injection and sublingual) | Low-cost compounded GLP-1 with plain compounding disclosures |
| Medication type | Compounded semaglutide and tirzepatide | Compounded semaglutide and tirzepatide — sublingual/oral and once-weekly injection |
| Pricing model | All-inclusive monthly price by medication format | Monthly auto-refill subscription; dose-tier 'starting at' entry pricing; medical-necessity gated |
| Semaglutide price | From $179.10/mo (sublingual) to $297/mo (injection), all-inclusive | Compounded — sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing) |
| Tirzepatide price | From $224.10/mo (sublingual) to $399/mo (injection), all-inclusive | Compounded — injectable from $199/mo; oral lozenge from $199/mo (lozenge only if a GLP-1 injection fails or can't be used) |
| Key watchout | Pricing varies by format and page — product-page 'all-inclusive' rates differ from homepage promo cards; confirm your format's rate at checkout | Entry prices are the lowest-dose auto-refill rate — higher doses cost more, so confirm your dose at intake. Oral/sublingual and lozenge options require you to have failed or be unable to use an injectable GLP-1. |
When to choose Direct Meds
- You want a specific format — injection or sublingual — at a clear all-inclusive price
- You're already familiar with GLP-1 dosing and side-effect management
- You don't need a coach or a heavy-touch clinical team
- You want a no-frills, predictable monthly bill
Check current Direct Meds pricing →
When to choose Strut Health
- You want low-cost compounded semaglutide or tirzepatide with medication included
- You value upfront 'compounded / not FDA-approved' disclosures and a PCAB-accredited pharmacy
- You're comfortable with async-only care (no video visit) and a medical-necessity screen
- You want to cancel, pause, or delay your subscription anytime
Check current Strut Health pricing →
Full reviews
Frequently asked questions
Is Direct Meds cheaper than Strut Health?
Strut Health starts lower on semaglutide (Compounded — sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing)). Strut Health starts lower on tirzepatide (Compounded — injectable from $199/mo; oral lozenge from $199/mo (lozenge only if a GLP-1 injection fails or can't be used)). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide — Direct Meds or Strut Health?
Strut Health starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are Direct Meds and Strut Health compounded or brand-name?
Direct Meds offers compounded semaglutide and tirzepatide. Strut Health offers compounded semaglutide and tirzepatide — sublingual/oral and once-weekly injection. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Direct Meds to Strut Health?
Yes — switching between Direct Meds and Strut Health is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Direct Meds and Strut Health to other programs
- Direct Meds vs ShedRx · Strut Health vs ShedRx
- Direct Meds vs TMates · Strut Health vs TMates
- Direct Meds vs Sprout Health · Strut Health vs Sprout Health
- Direct Meds vs Mochi Health · Strut Health vs Mochi Health
- Direct Meds vs Henry Meds · Strut Health vs Henry Meds
- Direct Meds vs Calibrate · Strut Health vs Calibrate
- Direct Meds vs Embody · Strut Health vs Embody
- Direct Meds vs Found · Strut Health vs Found
Related guides
RangeYourself is reader-supported. We may earn a commission when you click on certain links — at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like $179.10/mo (sublingual) to $297/mo (injection), all-inclusive and Compounded — sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing) are starting tiers, not your guaranteed long-term cost.