Quick answer
Trimi and Yucca Health both offer GLP-1 telehealth, but they package medication, support, and pricing differently. The right choice depends on whether you weight cost, clinical touch, or formulation flexibility highest.
Side-by-side comparison
| Feature | Trimi | Yucca Health |
|---|---|---|
| Best for | Lowest-cost compounded GLP-1 on an annual plan with a plain 503A disclosure | Low advertised entry price on compounded GLP-1 with plain FDA disclosures and all-50-state provider coverage |
| Medication type | Compounded semaglutide and compounded tirzepatide, once-weekly at-home injection | Compounded semaglutide and tirzepatide, once-weekly injection ('Semaglutide+' / 'Tirzepatide+'); also sells NAD+ and Sermorelin (out of registry scope) |
| Pricing model | Flat-membership subscription billed yearly (annual commitment tier); one price covers medication, clinician visits, check-ins, shipping; no separate membership fee; no insurance | 6-month prescription plans billed monthly/quarterly/6-month; advertised new-patient entry pricing; full pricing shared after intake |
| Semaglutide price | Compounded, $99/mo on the annual plan, BILLED YEARLY ($1,188/yr up front). Verified 2026-07-14. | Compounded, '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated) |
| Tirzepatide price | Compounded, $125/mo on the annual plan (billed yearly). Verified 2026-07-14. | Compounded, '$258 /mo 6 month supply' (new-patient 6-month plan entry rate; full pricing intake-gated) |
| Key watchout | The $99/mo semaglutide and $125/mo tirzepatide rates are the ANNUAL plan, BILLED YEARLY (semaglutide = $1,188 charged up front). A month-to-month rate is not published, confirm billing terms before enrolling. | The $146/mo figure is a NEW-PATIENT 'as low as' rate on a 6-month semaglutide plan, shown site-wide with an 'Exclusive Lifetime Offer' promo code (YUCCA4LIFE), Yucca's own FAQ says full pricing 'is shared after intake once eligibility is confirmed.' Confirm your dose's ongoing rate at intake. Pharmacies are not named. |
When to choose Trimi
- You want the lowest-cost compounded semaglutide ($99/mo) or tirzepatide ($125/mo) with everything bundled
- You’re comfortable with an annual plan billed yearly ($1,188 up front for semaglutide)
- You value an upfront '503A compounding pharmacy' and 'not FDA-approved' disclosure
- You want care via a 50-state clinical network (Arora Health) with free shipping
When to choose Yucca Health
- You want a low advertised entry price on compounded semaglutide or tirzepatide
- You value an upfront 'not FDA-approved' compounding disclosure in the FAQ
- You want provider coverage in all 50 states with free 2-day shipping
- You're comfortable confirming your exact ongoing rate at intake (pricing beyond the entry offer is shared after eligibility)
Check current Yucca Health pricing →
Full reviews
Frequently asked questions
Is Trimi cheaper than Yucca Health?
Trimi starts lower on semaglutide (Compounded, $99/mo on the annual plan, BILLED YEARLY ($1,188/yr up front). Verified 2026-07-14.). Trimi starts lower on tirzepatide (Compounded, $125/mo on the annual plan (billed yearly). Verified 2026-07-14.). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide, Trimi or Yucca Health?
Trimi starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are Trimi and Yucca Health compounded or brand-name?
Trimi offers compounded semaglutide and compounded tirzepatide, once-weekly at-home injection. Yucca Health offers compounded semaglutide and tirzepatide, once-weekly injection ('semaglutide+' / 'tirzepatide+'); also sells nad+ and sermorelin (out of registry scope). If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Trimi to Yucca Health?
Yes, switching between Trimi and Yucca Health is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Trimi and Yucca Health to other programs
- Trimi vs ShedRx · Yucca Health vs ShedRx
- Trimi vs TMates · Yucca Health vs TMates
- Trimi vs Direct Meds · Yucca Health vs Direct Meds
- Trimi vs Sprout Health · Yucca Health vs Sprout Health
- Trimi vs Mochi Health · Yucca Health vs Mochi Health
- Trimi vs Henry Meds · Yucca Health vs Henry Meds
- Trimi vs Calibrate · Yucca Health vs Calibrate
- Trimi vs Embody · Yucca Health vs Embody
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RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like Compounded, $99/mo on the annual plan, BILLED YEARLY ($1,188/yr up front). Verified 2026-07-14. and Compounded, '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated) are starting tiers, not your guaranteed long-term cost.