Quick answer
Sesame Care typically wins on sticker price for compounded GLP-1, while ShedRx bundles more clinical support and often a wider menu of options. Choose Sesame Care if you're price-first; choose ShedRx if you want hands-on prescribing or brand-name access.
Side-by-side comparison
| Feature | Sesame Care | ShedRx |
|---|---|---|
| Best for | Brand-name GLP-1 with insurance support, subscription program | Broad GLP-1 menu and multiple formats |
| Medication type | Brand-name GLP-1 (Wegovy, Zepbound, Ozempic, Foundayo) via subscription program | Compounded and brand-name options |
| Pricing model | Monthly program subscription; medication billed separately | Starting prices by product |
| Semaglutide price | Wegovy® pill from $149/mo cash + program subscription $59/mo (12-month commitment) to $99/mo (month-to-month, no commitment), full tier ladder verified 2026-07-25 on sesamecare.com/service/online-weight-loss-program (FAQ: 'Month-to-Month Plan: Billed every month at $99 per month') | From $249/mo (compounded injection); GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo, verified 2026-07-21 on tryshed.com/products/category/weight-loss |
| Tirzepatide price | Zepbound® from $299/mo cash + program subscription $59/mo (12-month commitment) to $99/mo (month-to-month, no commitment), medication billed separately, verified 2026-07-25 | From $349/mo (compounded injection), verified 2026-07-21 on tryshed.com/products/category/weight-loss |
| Key watchout | Program fee excludes medication, total cost depends on medication path and coverage | Verify higher-dose pricing and exact formulation before checkout |
When to choose Sesame Care
- You want brand-name medication (Wegovy, Zepbound, Ozempic, Foundayo) rather than compounded
- You already have insurance and want a clinician who can prescribe brand-name GLP-1
- You'd use the annual plan to bring the program fee down to $59/month
- You're comfortable with a program fee that's separate from medication cost
Check current Sesame Care pricing →
When to choose ShedRx
- You want both compounded and brand-name options on one menu
- You prefer multiple formulation formats (injection, oral, sublingual where offered)
- You're starting at a low dose and want a low entry price
- You value being able to switch products without changing programs
Check current ShedRx pricing →
Full reviews
Frequently asked questions
Is Sesame Care cheaper than ShedRx?
Sesame Care starts lower on semaglutide (Wegovy® pill from $149/mo cash + program subscription $59/mo (12-month commitment) to $99/mo (month-to-month, no commitment), full tier ladder verified 2026-07-25 on sesamecare.com/service/online-weight-loss-program (FAQ: 'Month-to-Month Plan: Billed every month at $99 per month')). Sesame Care starts lower on tirzepatide (Zepbound® from $299/mo cash + program subscription $59/mo (12-month commitment) to $99/mo (month-to-month, no commitment), medication billed separately, verified 2026-07-25). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide, Sesame Care or ShedRx?
Sesame Care starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are Sesame Care and ShedRx compounded or brand-name?
Sesame Care offers brand-name glp-1 (wegovy, zepbound, ozempic, foundayo) via subscription program. ShedRx offers compounded and brand-name options. If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Sesame Care to ShedRx?
Yes, switching between Sesame Care and ShedRx is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Sesame Care and ShedRx to other programs
- Sesame Care vs TMates · ShedRx vs TMates
- Sesame Care vs Direct Meds · ShedRx vs Direct Meds
- Sesame Care vs Sprout Health · ShedRx vs Sprout Health
- Sesame Care vs Mochi Health · ShedRx vs Mochi Health
- Sesame Care vs Henry Meds · ShedRx vs Henry Meds
- Sesame Care vs Calibrate · ShedRx vs Calibrate
- Sesame Care vs Embody · ShedRx vs Embody
- Sesame Care vs Found · ShedRx vs Found
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RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like Wegovy® pill from $149/mo cash + program subscription $59/mo (12-month commitment) to $99/mo (month-to-month, no commitment), full tier ladder verified 2026-07-25 on sesamecare.com/service/online-weight-loss-program (FAQ: 'Month-to-Month Plan: Billed every month at $99 per month') and $249/mo (compounded injection); GLP-1 lozenges from $199/mo; GLP-1 liquid drops from $229/mo; oral semaglutide liposomal tablets from $299/mo, verified 2026-07-21 on tryshed.com/products/category/weight-loss are starting tiers, not your guaranteed long-term cost.