Quick answer
Sesame Care and Yucca Health both offer GLP-1 telehealth, but they package medication, support, and pricing differently. The right choice depends on whether you weight cost, clinical touch, or formulation flexibility highest.
Side-by-side comparison
| Feature | Sesame Care | Yucca Health |
|---|---|---|
| Best for | Brand-name GLP-1 with insurance support, subscription program | Low advertised entry price on compounded GLP-1 with plain FDA disclosures and all-50-state provider coverage |
| Medication type | Brand-name GLP-1 (Wegovy, Zepbound, Ozempic, Foundayo) via subscription program | Compounded semaglutide and tirzepatide, once-weekly injection ('Semaglutide+' / 'Tirzepatide+'); also sells NAD+ and Sermorelin (out of registry scope) |
| Pricing model | Monthly program subscription; medication billed separately | 6-month prescription plans billed monthly/quarterly/6-month; advertised new-patient entry pricing; full pricing shared after intake |
| Semaglutide price | Wegovy® pill from $149/mo cash + program subscription $59/mo (12-month commitment) to $99/mo (month-to-month, no commitment), full tier ladder verified 2026-07-25 on sesamecare.com/service/online-weight-loss-program (FAQ: 'Month-to-Month Plan: Billed every month at $99 per month') | Compounded, '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated) |
| Tirzepatide price | Zepbound® from $299/mo cash + program subscription $59/mo (12-month commitment) to $99/mo (month-to-month, no commitment), medication billed separately, verified 2026-07-25 | Compounded, '$258 /mo 6 month supply' (new-patient 6-month plan entry rate; full pricing intake-gated) |
| Key watchout | Program fee excludes medication, total cost depends on medication path and coverage | The $146/mo figure is a NEW-PATIENT 'as low as' rate on a 6-month semaglutide plan, shown site-wide with an 'Exclusive Lifetime Offer' promo code (YUCCA4LIFE), Yucca's own FAQ says full pricing 'is shared after intake once eligibility is confirmed.' Confirm your dose's ongoing rate at intake. Pharmacies are not named. |
When to choose Sesame Care
- You want brand-name medication (Wegovy, Zepbound, Ozempic, Foundayo) rather than compounded
- You already have insurance and want a clinician who can prescribe brand-name GLP-1
- You'd use the annual plan to bring the program fee down to $59/month
- You're comfortable with a program fee that's separate from medication cost
Check current Sesame Care pricing →
When to choose Yucca Health
- You want a low advertised entry price on compounded semaglutide or tirzepatide
- You value an upfront 'not FDA-approved' compounding disclosure in the FAQ
- You want provider coverage in all 50 states with free 2-day shipping
- You're comfortable confirming your exact ongoing rate at intake (pricing beyond the entry offer is shared after eligibility)
Check current Yucca Health pricing →
Full reviews
Frequently asked questions
Is Sesame Care cheaper than Yucca Health?
Yucca Health starts lower on semaglutide (Compounded, '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated)). Yucca Health starts lower on tirzepatide (Compounded, '$258 /mo 6 month supply' (new-patient 6-month plan entry rate; full pricing intake-gated)). Higher doses can shift the picture, so confirm pricing at the dose you're likely to use long-term.
Which is better for semaglutide or tirzepatide, Sesame Care or Yucca Health?
Yucca Health starts lower on both semaglutide and tirzepatide based on listed entry pricing. That said, the right pick is the program whose support model and formulation match what you actually need.
Are Sesame Care and Yucca Health compounded or brand-name?
Sesame Care offers brand-name glp-1 (wegovy, zepbound, ozempic, foundayo) via subscription program. Yucca Health offers compounded semaglutide and tirzepatide, once-weekly injection ('semaglutide+' / 'tirzepatide+'); also sells nad+ and sermorelin (out of registry scope). If you specifically want brand-name Wegovy or Zepbound, lean toward whichever explicitly supports brand access; if compounded is fine, both can typically meet that need.
Can I switch from Sesame Care to Yucca Health?
Yes, switching between Sesame Care and Yucca Health is straightforward in most states. You typically finish your current month, complete a new intake with the other provider, and they handle the prescription. Watch for overlap on auto-renewal billing and confirm any dose-tier or formulation differences with the new clinician before your next shipment.
Compare Sesame Care and Yucca Health to other programs
- Sesame Care vs ShedRx · Yucca Health vs ShedRx
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- Sesame Care vs Direct Meds · Yucca Health vs Direct Meds
- Sesame Care vs Sprout Health · Yucca Health vs Sprout Health
- Sesame Care vs Mochi Health · Yucca Health vs Mochi Health
- Sesame Care vs Henry Meds · Yucca Health vs Henry Meds
- Sesame Care vs Calibrate · Yucca Health vs Calibrate
- Sesame Care vs Embody · Yucca Health vs Embody
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RangeYourself is reader-supported. We may earn a commission when you click on certain links, at no extra cost to you. Editorial recommendations are made independently. Pricing reflects publicly listed entry tiers as of May 2026 and may change. Numbers like Wegovy® pill from $149/mo cash + program subscription $59/mo (12-month commitment) to $99/mo (month-to-month, no commitment), full tier ladder verified 2026-07-25 on sesamecare.com/service/online-weight-loss-program (FAQ: 'Month-to-Month Plan: Billed every month at $99 per month') and Compounded, '$146 /mo 6 month supply' ('*New Patients, Semaglutide 6-month plan'; 'as low as' entry rate, promo code YUCCA4LIFE '$146 /mo For life' active; full pricing intake-gated) are starting tiers, not your guaranteed long-term cost.