Tirzepatide is the active ingredient in both Zepbound (FDA-approved for chronic weight management) and compounded tirzepatide products. Against Zepbound’s list price the cash-pay gap looks large (~5x), but Eli Lilly’s LillyDirect self-pay vials ($299–$449/month) have narrowed it close to compounded telehealth pricing ($219–$349/month), compare the path you’d actually use, not the list price.
Who this list is for
Researchers deciding between compounded tirzepatide and brand-name Zepbound.
Ranked programs
| Provider | All-in monthly | Semaglutide | Tirzepatide | Compounded vs brand | Insurance accepted? | Last verified | Price source | |
|---|---|---|---|---|---|---|---|---|
| $79/mo + Rxintro: $39 first month | Membership $79/mo + compounded semaglutide $99/mo (all doses); brand-name billed via insurance | Membership $79/mo + compounded tirzepatide $199/mo (all doses); brand-name billed via insurance | Both | Yes | joinmochi.com ↗ | See pricing → | ||
| $99/mo | Compounded, $99/mo on the annual plan, BILLED YEARLY ($1,188/yr up front). Verified 2026-07-14. | Compounded, $125/mo on the annual plan (billed yearly). Verified 2026-07-14. | Compounded | No | trytrimi.com ↗ | See pricing → | ||
| $99/mo | Compounded, $99–$129/mo (same price at every dose): 12-mo $99, 6-mo $109, 3-mo $119, 1-mo $129. Verified 2026-07-14. | Compounded, $139–$179/mo (same price at every dose): 12-mo $139, 6-mo $149, 3-mo $159, 1-mo $179. Verified 2026-07-14. | Compounded | No | bmimd.com ↗ | See pricing → | ||
| $158/mo | From $158/mo (compounded semaglutide, 12-month plan; $249/mo month-to-month); medication and visits included | From $167/mo (compounded tirzepatide, 12-month plan; $297/mo month-to-month) | Compounded | No | tmates.com ↗ | See pricing → | ||
| $169/mo | From $169/mo on a 12-month plan paid up-front ($289/mo month-to-month), cash-pay, compounded meds included; with insurance $99/mo prepaid annual or $199/mo monthly + copay (typically ~$30). Verified 2026-07-25 on joinfound.com/plans-and-pricing. | From $169/mo on a 12-month plan paid up-front ($289/mo month-to-month), cash-pay, compounded meds included; with insurance $99/mo prepaid annual or $199/mo monthly + copay (typically ~$30). Verified 2026-07-25 on joinfound.com/plans-and-pricing. | Both | Yes | joinfound.com ↗ | See pricing → | ||
| $179/mo | From $179/mo | From $179/mo | Compounded | No | henrymeds.com ↗ | See pricing → |
Why we ranked them this way
- Brand-name Zepbound without insurance: about $1,086/month list price, but Eli Lilly’s LillyDirect self-pay single-dose vials run $299/month (2.5mg), $399/month (5mg), and $449/month (7.5mg and up). Source: lilly.com / zepbound.lilly.com, as of June 2026.
- Brand-name Zepbound with insurance: $25–$75 copay if covered and prior auth approved.
- Compounded tirzepatide cash-pay: $219–$349/month with medication included at most reputable telehealth programs.
- LillyDirect vial pricing has narrowed the brand-vs-compounded gap on tirzepatide compared to a year ago, confirm current LillyDirect rates if you’re comparing.
The picks in detail
Mochi Health
Best for: Brand-name access where insurance can apply.
Watchout: Final cost depends heavily on insurance and pharmacy.
Pricing: $79/mo membership + medication, semaglutide membership $79/mo + compounded semaglutide $99/mo (all doses); brand-name billed via insurance, tirzepatide membership $79/mo + compounded tirzepatide $199/mo (all doses); brand-name billed via insurance.
Trimi
Best for: Lowest-cost compounded GLP-1 on an annual plan with a plain 503A disclosure.
Watchout: The $99/mo semaglutide and $125/mo tirzepatide rates are the ANNUAL plan, BILLED YEARLY (semaglutide = $1,188 charged up front). A month-to-month rate is not published, confirm billing terms before enrolling..
Pricing: $99/mo all-in (medication included), semaglutide compounded, $99/mo on the annual plan, billed yearly ($1,188/yr up front). verified 2026-07-14., tirzepatide compounded, $125/mo on the annual plan (billed yearly). verified 2026-07-14..
bmiMD
Best for: Low-cost compounded GLP-1 with a named 503A pharmacy and flat per-dose pricing.
Watchout: The lowest advertised rate ($99/mo semaglutide, $139/mo tirzepatide) is the 12-month commitment tier; month-to-month is $129/mo semaglutide and $179/mo tirzepatide. 'Same price at every dose', the price varies by plan length, not by dose..
Pricing: $99/mo all-in (medication included), semaglutide compounded, $99–$129/mo (same price at every dose): 12-mo $99, 6-mo $109, 3-mo $119, 1-mo $129. verified 2026-07-14., tirzepatide compounded, $139–$179/mo (same price at every dose): 12-mo $139, 6-mo $149, 3-mo $159, 1-mo $179. verified 2026-07-14..
TMates
Best for: Compounded GLP-1 with hands-on clinical touch.
Watchout: The $158 headline is the compounded SEMAGLUTIDE plan (12-month term; $249/mo month-to-month). Tirzepatide costs more ($167/mo on a 12-month plan, $297 month-to-month), confirm your product and term at checkout.
Pricing: $158/mo all-in (medication included), semaglutide from $158/mo (compounded semaglutide, 12-month plan; $249/mo month-to-month); medication and visits included, tirzepatide from $167/mo (compounded tirzepatide, 12-month plan; $297/mo month-to-month).
Found
Best for: Personalized prescribing across drug classes.
Watchout: Final medication may not be GLP-1 if clinician recommends otherwise.
Pricing: $169/mo all-in (medication included), semaglutide from $169/mo on a 12-month plan paid up-front ($289/mo month-to-month), cash-pay, compounded meds included; with insurance $99/mo prepaid annual or $199/mo monthly + copay (typically ~$30). verified 2026-07-25 on joinfound.com/plans-and-pricing., tirzepatide from $169/mo on a 12-month plan paid up-front ($289/mo month-to-month), cash-pay, compounded meds included; with insurance $99/mo prepaid annual or $199/mo monthly + copay (typically ~$30). verified 2026-07-25 on joinfound.com/plans-and-pricing..
Henry Meds
Best for: Simple compounded program with broad availability.
Watchout: Limited brand-name path if you later want Wegovy/Zepbound.
Pricing: $179/mo all-in (medication included), semaglutide from $179/mo, tirzepatide from $179/mo.
Frequently asked questions
Is compounded tirzepatide the same as Zepbound?
Both contain tirzepatide. Zepbound is FDA-approved for chronic weight management and produced by Eli Lilly. Compounded tirzepatide is prepared by state-licensed 503A pharmacies (or 503B outsourcing facilities) and is not individually FDA-approved. The FDA declared the tirzepatide shortage resolved in December 2024, and compounders generally may no longer make products that are “essentially a copy” of Zepbound unless a prescriber documents a change that produces a significant difference for an individual patient.
Is LillyDirect cheaper than compounded tirzepatide?
At entry doses, LillyDirect single-dose vials ($399–$549/month) are within range of compounded tirzepatide ($219–$349/month) but still typically more expensive. At higher doses LillyDirect pricing rises further.
Should I switch from compounded to Zepbound?
If your insurance covers brand-name Zepbound at a low copay, switching is reasonable. If you’re cash-pay, compounded tirzepatide is typically the more affordable path even after considering LillyDirect.
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