Compounded semaglutide is marketed as using the same active ingredient as brand-name Wegovy, but it is not an FDA-approved finished product, and the FDA warns that some compounded versions use salt forms (semaglutide sodium or acetate) that are different active ingredients than the approved drug. The two paths also cost very different amounts depending on whether you have insurance and which path you choose.
Who this list is for
Researchers deciding between compounded semaglutide and brand-name Wegovy.
Ranked programs
| Provider | All-in monthly | Semaglutide | Tirzepatide | Compounded vs brand | Insurance accepted? | Last verified | Price source | |
|---|---|---|---|---|---|---|---|---|
| $74/mo + Rxintro: $25 first month (66% off promo on the 12-month plan) | Brand-name only, billed separately from membership, self-pay Wegovy® pill from $149/mo, Wegovy® pen from $199/mo, Ozempic® from $149/mo (pill) / $199/mo (pen), Foundayo® (orforglipron) from $149/mo; separate Med+ membership required (verified 2026-07-16 on weightwatchers.com/us/weight-loss-medication) | Brand-name only, billed separately, self-pay Zepbound® from $299/mo; separate Med+ membership required (verified 2026-07-16) | Both | Yes | weightwatchers.com ↗ | See pricing → | ||
| $79/mo + Rxintro: $39 first month | Membership $79/mo + compounded semaglutide $99/mo (all doses); brand-name billed via insurance | Membership $79/mo + compounded tirzepatide $199/mo (all doses); brand-name billed via insurance | Both | Yes | joinmochi.com ↗ | See pricing → | ||
| $99/mo(oral sublingual; injectable semaglutide is $149/mo)tied at $99/mo | Compounded, sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing) | Compounded, injectable from $199/mo; oral lozenge from $199/mo (lozenge only if a GLP-1 injection fails or can't be used) | Compounded | No | struthealth.com ↗ | See pricing → | ||
| $99/motied at $99/mo | Compounded, $99–$129/mo (same price at every dose): 12-mo $99, 6-mo $109, 3-mo $119, 1-mo $129. Verified 2026-07-14. | Compounded, $139–$179/mo (same price at every dose): 12-mo $139, 6-mo $149, 3-mo $159, 1-mo $179. Verified 2026-07-14. | Compounded | No | bmimd.com ↗ | See pricing → | ||
| $99/motied at $99/mo | Compounded, $99/mo on the annual plan, BILLED YEARLY ($1,188/yr up front). Verified 2026-07-14. | Compounded, $125/mo on the annual plan (billed yearly). Verified 2026-07-14. | Compounded | No | trytrimi.com ↗ | See pricing → | ||
| $99/motied at $99/mo | Compounded, $99/mo on the 12-month plan; from $133/mo on the 3-month plan, verified 2026-07-18 on healthrx.com. Same price at every dose. | Compounded, $179/mo on the 12-month plan; from $209/mo on the 3-month plan, verified 2026-07-18 on healthrx.com. Same price at every dose. | Compounded | No | healthrx.com ↗ | See pricing → |
- Strut Health, the $99 rate is oral sublingual; injectable semaglutide is $149/mo; monthly auto-refill; 49 states (excludes AR); cancel, pause, or delay anytime (48h notice).
- bmiMD, select states, confirm at signup; $50 cancellation fee; no partial refunds, all sales final.
- Trimi, billed yearly, paid up front (~$1,188/yr, or buy-now-pay-later; paying monthly costs more); all 50 states; 6-month money-back if you don’t lose weight.
- HealthRX, billed monthly, no upfront lump sum; all 50 states; one-click cancel anytime, no fee; unshipped doses refunded; refund if a provider doesn’t approve you (dispensed medication is final).
Why we ranked them this way
- Brand-name Wegovy without insurance: about $1,350/month list price, but Novo Nordisk’s NovoCare cash-pay price is now $349/month for self-pay patients ($199/month for the first two starter-dose fills during a limited NovoCare promotional period, verify the current end date at novocare.com); the Wegovy pill is $149/month. Source: wegovy.com / novocare.com, as of June 2026.
- Brand-name Wegovy with insurance: $25–$75 copay if your plan covers it and you clear prior authorization.
- Compounded semaglutide cash-pay: $149–$249/month with medication included at most reputable telehealth programs.
- For cash-pay patients, compounded semaglutide is often marketed as the lower-cost option, but brand-name Wegovy is also available to self-pay patients through Novo Nordisk’s NovoCare pharmacy. For insured patients with coverage, brand-name Wegovy may be cheaper out-of-pocket.
The picks in detail
WeightWatchers
Best for: Brand-name GLP-1 with behavioral program and insurance billing.
Watchout: Total cost depends on insurance, without coverage, brand-name medication is $500-$1,300/mo.
Pricing: $74/mo membership + medication, semaglutide brand-name only, billed separately from membership, self-pay wegovy® pill from $149/mo, wegovy® pen from $199/mo, ozempic® from $149/mo (pill) / $199/mo (pen), foundayo® (orforglipron) from $149/mo; separate med+ membership required (verified 2026-07-16 on weightwatchers.com/us/weight-loss-medication), tirzepatide brand-name only, billed separately, self-pay zepbound® from $299/mo; separate med+ membership required (verified 2026-07-16).
Mochi Health
Best for: Brand-name access where insurance can apply.
Watchout: Final cost depends heavily on insurance and pharmacy.
Pricing: $79/mo membership + medication, semaglutide membership $79/mo + compounded semaglutide $99/mo (all doses); brand-name billed via insurance, tirzepatide membership $79/mo + compounded tirzepatide $199/mo (all doses); brand-name billed via insurance.
Strut Health
Best for: Low-cost compounded GLP-1 with plain compounding disclosures.
Watchout: Entry prices are the lowest-dose auto-refill rate, higher doses cost more, so confirm your dose at intake. Oral/sublingual and lozenge options require you to have failed or be unable to use an injectable GLP-1..
Pricing: $99/mo all-in (medication included), semaglutide compounded, sublingual/oral from $99/mo, injectable from $149/mo (auto-refill 'starting at' entry-dose pricing), tirzepatide compounded, injectable from $199/mo; oral lozenge from $199/mo (lozenge only if a glp-1 injection fails or can't be used).
bmiMD
Best for: Low-cost compounded GLP-1 with a named 503A pharmacy and flat per-dose pricing.
Watchout: The lowest advertised rate ($99/mo semaglutide, $139/mo tirzepatide) is the 12-month commitment tier; month-to-month is $129/mo semaglutide and $179/mo tirzepatide. 'Same price at every dose', the price varies by plan length, not by dose..
Pricing: $99/mo all-in (medication included), semaglutide compounded, $99–$129/mo (same price at every dose): 12-mo $99, 6-mo $109, 3-mo $119, 1-mo $129. verified 2026-07-14., tirzepatide compounded, $139–$179/mo (same price at every dose): 12-mo $139, 6-mo $149, 3-mo $159, 1-mo $179. verified 2026-07-14..
Trimi
Best for: Lowest-cost compounded GLP-1 on an annual plan with a plain 503A disclosure.
Watchout: The $99/mo semaglutide and $125/mo tirzepatide rates are the ANNUAL plan, BILLED YEARLY (semaglutide = $1,188 charged up front). A month-to-month rate is not published, confirm billing terms before enrolling..
Pricing: $99/mo all-in (medication included), semaglutide compounded, $99/mo on the annual plan, billed yearly ($1,188/yr up front). verified 2026-07-14., tirzepatide compounded, $125/mo on the annual plan (billed yearly). verified 2026-07-14..
HealthRX
Best for: A low, transparent flat price on compounded GLP-1 with no insurance and fast shipping.
Watchout: The lowest advertised rate requires the 12-month commitment plan; the 3-month plan is the higher entry tier, and any 1-month option is not publicly priced (and earns RY no payout). Confirm your plan term and dose price at checkout..
Pricing: $99/mo all-in (medication included), semaglutide compounded, $99/mo on the 12-month plan; from $133/mo on the 3-month plan, verified 2026-07-18 on healthrx.com. same price at every dose., tirzepatide compounded, $179/mo on the 12-month plan; from $209/mo on the 3-month plan, verified 2026-07-18 on healthrx.com. same price at every dose..
Frequently asked questions
Is compounded semaglutide the same as Wegovy?
Both are based on semaglutide, but the FDA warns that some compounded versions use salt forms (semaglutide sodium or acetate) it considers different active ingredients than the approved drug, and that compounded semaglutide should not be described as the same as Wegovy. Wegovy is FDA-approved for chronic weight management and produced by Novo Nordisk. Compounded semaglutide is prepared by state-licensed 503A pharmacies (or 503B outsourcing facilities) and is not individually FDA-approved. Compounding was permitted while semaglutide was in shortage, but the FDA declared that shortage resolved on February 21, 2025, and the enforcement-discretion periods have since ended (April 22, 2025 for 503A pharmacies; May 22, 2025 for 503B facilities). Compounders generally may no longer make products that are “essentially a copy” of Wegovy unless a prescriber documents a change that produces a significant difference for an individual patient.
Does compounded semaglutide work as well as Wegovy?
Clinical evidence is limited because compounded medications are not individually FDA-reviewed or studied for effectiveness at scale, so their results cannot be assumed to match the branded product’s clinical-trial evidence. Always verify pharmacy sourcing and have a clinician evaluate your case.
Should I choose Wegovy over compounded if I have insurance?
If your insurance covers brand-name Wegovy with a low copay, brand-name is typically the better-supported choice. If your insurance doesn’t cover it (or denies prior auth), compounded semaglutide is often a lower-cost cash-pay path, though Novo Nordisk’s NovoCare self-pay pricing for brand-name Wegovy has narrowed that gap, so compare the path you’d actually use.
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